Frontiers in Medicine | Infectious Diseases: Pathogenesis and Therapy

Case Report

Published on 12 Jan 2026

Isavuconazole in the treatment of acute invasive fungal sinusitis: two case reports and literature review

in Infectious Diseases: Pathogenesis and Therapy

Kun Zhao
Yuwan Song
Huhuifen He
Fengxin Yang
He Zhao
Yan Wang
Li Wang
Yan Wang
Yan Sun

Frontiers in Medicine

doi 10.3389/fmed.2025.1700685

727 views

Original Research

Published on 12 Jan 2026

Development of a short-term prognostic model for hepatitis B-related acute-on-chronic liver failure in a dual-center cohort

in Infectious Diseases: Pathogenesis and Therapy

Huaidong Deng
Ruili Bao
Yanxue Lu
Hui Xu
Rongkuan Li
Jia Yao

Frontiers in Medicine

doi 10.3389/fmed.2025.1688479

761 views

Original Research

Published on 09 Jan 2026

Clinical and CT image features for survival prediction in severe pneumonia during the SARS-CoV-2 Omicron wave

in Infectious Diseases: Pathogenesis and Therapy

Wei Xu
Jing Zhao
Teng Wang
Jingjiang Lai
Jingliang Wang
Fengxian Jiang
Cuiyan Wang
Guobin Fu

Frontiers in Medicine

doi 10.3389/fmed.2025.1663710

611 views

Brief Research Report

Published on 09 Jan 2026

Genetic patterns related to von Willebrand factor: implications on the need for mechanical ventilation, severity, and death in COVID-19

in Infectious Diseases: Pathogenesis and Therapy

José López Castro
Silvia Diz-de Almeida
Manuel L. López Reboiro
Cristina Sardiña González
Jose A. Riancho
Augusto Rojas-Martinez
Pablo Lapunzina
Carlos Flores
Raquel Cruz
Angel Carracedo

Frontiers in Medicine

doi 10.3389/fmed.2025.1690764

1,189 views

Case Report

Published on 08 Jan 2026

Case Report: Massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman

in Infectious Diseases: Pathogenesis and Therapy

Jiaqi Chen
Zejin Zhao
Kunyu Huang
Liyong Zhang
Jinhua Cui
Ziyu Bai
Aijun Yu
Jian Li
Zhuqing Zhang
Kai Chen

Frontiers in Medicine

doi 10.3389/fmed.2025.1713210

592 views

Original Research

Published on 08 Jan 2026

A meta-analysis of controlled clinical trials comparing peginterferon-α plus nucleos(t)ide analogs versus peginterferon-α monotherapy for HBsAg clearance or seroconversion in patients with chronic hepatitis B

in Infectious Diseases: Pathogenesis and Therapy

Shuyao Zhu
Zhilin Yang
Yuanyuan Wang
Xuebin Cai
Chaochao Qin

Frontiers in Medicine

doi 10.3389/fmed.2025.1716225

686 views

Case Report

Published on 08 Jan 2026

Case Report: NGS-guided rapid diagnosis of tuberculous otitis media—a rare case of dual-site Mycobacterium tuberculosis infection

in Infectious Diseases: Pathogenesis and Therapy

Yang Gao
Xinlei Wang
Yi Cheng
Shengxin Ye
Xin Dong
Chi Zhu

Frontiers in Medicine

doi 10.3389/fmed.2025.1734666

712 views

Original Research

Published on 07 Jan 2026

Machine learning-based approach to guide the choice between baricitinib and tocilizumab in critical COVID-19 pneumonia treatment: a retrospective cohort study

in Infectious Diseases: Pathogenesis and Therapy

Euijin Chang
Myung-Soo Kim
Se Yoon Park
Kyungsup Kwon
Hyeon Mu Jang
So Yun Lim
Seongman Bae
Jiwon Jung
Min Jae Kim
Yong Pil Chong

Frontiers in Medicine

doi 10.3389/fmed.2025.1734109

749 views

Review

Published on 07 Jan 2026

Immunological testing and machine learning in detecting latent tuberculosis among high-risk groups (nature review)

in Infectious Diseases: Pathogenesis and Therapy

Anna Starshinova
Adilya Sabirova
Igor Kudryavtsev
Artem Rubinstein
Leonid P. Churilov
Ekaterina Belyaeva
Kulpina Anastasia
Raul A. Sharipov
Ravil K. Tukfatullin
Nikolay Nikolenko

Frontiers in Medicine

doi 10.3389/fmed.2025.1710960

929 views

Original Research

Published on 07 Jan 2026

Solving the diagnostic dilemma in bone infections: metagenomic next generation sequencing enhances pathogen identification accuracy

in Infectious Diseases: Pathogenesis and Therapy

Jiheng Xiao
Congli Pu
Xianglong Zhou
Xiaokang Zhang
Shanshan Zhang
Puxin Yang
Yingze Zhang
Liming Xiong

Frontiers in Medicine

doi 10.3389/fmed.2025.1699607

987 views

Correction

Published on 06 Jan 2026

Correction: A rare case of Clostridium paraputrificum bloodstream infection in a patient with intestinal necrosis: case report and literature review

in Infectious Diseases: Pathogenesis and Therapy

Frontiers Production Office

Frontiers in Medicine

doi 10.3389/fmed.2025.1761583

406 views

Case Report

Published on 06 Jan 2026

First case report of Shewanella indica isolated from a hospitalized patient in Serbia

in Infectious Diseases: Pathogenesis and Therapy

Brankica Filipić
Vladimir Žugić
Majda Golob
Martina Hrast Rambaher
Lidija Bošković
Marina T. Milenković

Frontiers in Medicine

doi 10.3389/fmed.2025.1715579

649 views

Perspective

Published on 06 Jan 2026

The development of a therapeutic strategy for post-acute sequelae of COVID-19 should be based on an efficient classification of pathogenesis

in Infectious Diseases: Pathogenesis and Therapy

Heng Wang
Li Shen
Song Xue

Frontiers in Medicine

doi 10.3389/fmed.2025.1718460

902 views

Case Report

Published on 06 Jan 2026

Rifampin monotherapy for multidrug-resistant Chryseobacterium indologenes meningitis unresponsive to trimethoprim-sulfamethoxazole: a case report and review of the literature

in Infectious Diseases: Pathogenesis and Therapy

Dongchuan Shao
Zhe Li
Zhiwei Cao
Zhou Yang
Wenbiao Huang
Kuairong Pu
Jun Wu
Nan Zhao

Frontiers in Medicine

doi 10.3389/fmed.2025.1701719

708 views

Systematic Review

Published on 05 Jan 2026

Association between stress hyperglycemia ratio and all-cause mortality among ICU patients with sepsis: a systematic review and meta-analysis

in Infectious Diseases: Pathogenesis and Therapy

Haohao Xie
Tian Hao
Ruirui Qi
Lin Zhang
Yuyan An
Donghui Jia
Hengyang Wang
Wenxiu Niu
Xiaomeng Han
Yuhan Sha

Frontiers in Medicine

doi 10.3389/fmed.2025.1741993

937 views

Original Research

Published on 05 Jan 2026

Elevated non-invasive liver fibrosis scores at admission are independent risk factors for severe COVID-19: a retrospective cohort study from 2020 to 2024

in Infectious Diseases: Pathogenesis and Therapy

Lucia Cabrejos Hirashima
Nicole E. Naiman
Amyn A. Malik
Mamta K. Jain

Frontiers in Medicine

doi 10.3389/fmed.2025.1727318

977 views

Case Report

Published on 05 Jan 2026

Gout of the iliopsoas muscle combined with tuberculosis infection causing persistent fever: a case report and literature review

in Infectious Diseases: Pathogenesis and Therapy

Mei-Ren Zhang
Jian-Hui Hu
Jian-hao Guan
Xiao Zeng
Hai-Yun Chen

Frontiers in Medicine

doi 10.3389/fmed.2025.1601095

1,210 views

Review

Accepted on 26 Dec 2025

Nocardia gipuzkoensis pneumonia diagnosed via metagenomic next-generation sequencing—Coinfection with COVID-19 was a blessing in disguise

in Infectious Diseases: Pathogenesis and Therapy

TianYu Sun
TengFei Yang
Bo Zhao

Frontiers in Medicine

131 views

Case Report

Published on 18 Dec 2025

Case Report: Severe psittacosis in an elderly patient without avian exposure: diagnosis via metagenomic next-generation sequencing and rapid response to doxycycline

in Infectious Diseases: Pathogenesis and Therapy

Xuxin Sun
Qihui Jiao
Xiaoyan Fu
Tingyi Xie
Wei Xie
Hong Cheng
Sheng Chen

Frontiers in Medicine

doi 10.3389/fmed.2025.1689333

1,137 views

Original Research

Published on 17 Dec 2025

Assessment of long COVID-19 symptoms and functional status: insights from a cross-sectional study

in Infectious Diseases: Pathogenesis and Therapy

Nicolás Escrivá
Laura Moreno-Galarraga
Elena Barado
María Gabriela Torres
Alejandro Fernández-Montero

Frontiers in Medicine

doi 10.3389/fmed.2025.1715786

1,274 views

Original Research

Published on 16 Dec 2025

Machine learning of immune-related laboratory indicators enables discrimination between pulmonary and extrapulmonary tuberculosis

in Infectious Diseases: Pathogenesis and Therapy

Shuanglin Gu
Yichen Guo
Han Jiang
Chen Yang
Tengyue Li
Xiuchang Ma
Wenxian Qian
Zihao Liang
Zheng Hu
Apeng Chen

Frontiers in Medicine

doi 10.3389/fmed.2025.1712073

1,481 views

Case Report

Published on 16 Dec 2025

Case Report: Psoas abscess caused by Carbapenem-Resistant Enterobacteriaceae in a CO poisoning patient

in Infectious Diseases: Pathogenesis and Therapy

Zhang Jia Cui
Wang Hao
Song Chengxin
Ma Xin Yue
Ma He Ping

Frontiers in Medicine

doi 10.3389/fmed.2025.1702821

1,199 views

Brief Research Report

Published on 15 Dec 2025

Identifying sepsis susceptibility genes in post-surgical patients using an artificial intelligence approach

in Infectious Diseases: Pathogenesis and Therapy

Fernando Vaquerizo-Villar
Tamara Hernandez-Beeftink
María Heredia-Rodríguez
Esther Gómez-Sánchez
Mario Lorenzo-López
Rocío López-Herrero
Miguel Bardaji-Carrillo
Álvaro Tamayo-Velasco
Marta Martín-Fernández
Laura Sánchez-de-Prada

Frontiers in Medicine

doi 10.3389/fmed.2025.1644800

2,167 views

Case Report

Published on 12 Dec 2025

Cryptococcal pericarditis with unexplained lymphadenopathy in an immunocompetent patient: a case report

in Infectious Diseases: Pathogenesis and Therapy

Jie Shu
Dongdong Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1688934

990 views

1,348 articles

articles

Isavuconazole in the treatment of acute invasive fungal sinusitis: two case reports and literature review

Development of a short-term prognostic model for hepatitis B-related acute-on-chronic liver failure in a dual-center cohort

Clinical and CT image features for survival prediction in severe pneumonia during the SARS-CoV-2 Omicron wave

Genetic patterns related to von Willebrand factor: implications on the need for mechanical ventilation, severity, and death in COVID-19

Case Report: Massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman

A meta-analysis of controlled clinical trials comparing peginterferon-α plus nucleos(t)ide analogs versus peginterferon-α monotherapy for HBsAg clearance or seroconversion in patients with chronic hepatitis B

Case Report: NGS-guided rapid diagnosis of tuberculous otitis media—a rare case of dual-site Mycobacterium tuberculosis infection

Machine learning-based approach to guide the choice between baricitinib and tocilizumab in critical COVID-19 pneumonia treatment: a retrospective cohort study

Immunological testing and machine learning in detecting latent tuberculosis among high-risk groups (nature review)

Solving the diagnostic dilemma in bone infections: metagenomic next generation sequencing enhances pathogen identification accuracy

Correction: A rare case of Clostridium paraputrificum bloodstream infection in a patient with intestinal necrosis: case report and literature review

First case report of Shewanella indica isolated from a hospitalized patient in Serbia

The development of a therapeutic strategy for post-acute sequelae of COVID-19 should be based on an efficient classification of pathogenesis

Rifampin monotherapy for multidrug-resistant Chryseobacterium indologenes meningitis unresponsive to trimethoprim-sulfamethoxazole: a case report and review of the literature

Association between stress hyperglycemia ratio and all-cause mortality among ICU patients with sepsis: a systematic review and meta-analysis

Elevated non-invasive liver fibrosis scores at admission are independent risk factors for severe COVID-19: a retrospective cohort study from 2020 to 2024

Gout of the iliopsoas muscle combined with tuberculosis infection causing persistent fever: a case report and literature review

Nocardia gipuzkoensis pneumonia diagnosed via metagenomic next-generation sequencing—Coinfection with COVID-19 was a blessing in disguise

Case Report: Severe psittacosis in an elderly patient without avian exposure: diagnosis via metagenomic next-generation sequencing and rapid response to doxycycline

Assessment of long COVID-19 symptoms and functional status: insights from a cross-sectional study

Machine learning of immune-related laboratory indicators enables discrimination between pulmonary and extrapulmonary tuberculosis

Case Report: Psoas abscess caused by Carbapenem-Resistant Enterobacteriaceae in a CO poisoning patient

Identifying sepsis susceptibility genes in post-surgical patients using an artificial intelligence approach

Cryptococcal pericarditis with unexplained lymphadenopathy in an immunocompetent patient: a case report