AUTHOR=Luo Zhao-Qing TITLE=Striking a Balance: Modulation of Host Cell Death Pathways by Legionella Pneumophila JOURNAL=Frontiers in Microbiology VOLUME=2 YEAR=2011 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2011.00036 DOI=10.3389/fmicb.2011.00036 ISSN=1664-302X ABSTRACT=
Programmed cell death is considered the ultimate solution for the host to eliminate infected cells, leading to the abolishment of the niche for microbial replication and the ablation of infection. Thus, it is not surprising that successful pathogens have evolved diverse strategies to reprogram the cell death pathways for their proliferation. Using effector proteins translocated by the Dot/Icm type IV secretion system, the facultative intracellular pathogen