AUTHOR=Echeverría-Vega Alex , Morales-Vicencio Pablo , Saez-Saavedra Camila , Alvarez María Alejandra , Gordillo Felipe , Del-Valle Rodrigo , Solís Ma. Eugenia , Araya Rubén 

TITLE=Characterization of the Bacteriophage vB_VorS-PVo5 Infection on Vibrio ordalii: A Model for Phage-Bacteria Adsorption in Aquatic Environments

JOURNAL=Frontiers in Microbiology

VOLUME=Volume 11 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2020.550979

DOI=10.3389/fmicb.2020.550979

ISSN=1664-302X

ABSTRACT=We designed mathematical first-order difference equations to model the initial stage of the bacteriophage infection dynamics in aquatic environments under laboratory conditions. Our model only requires knowing the initial bacterial and bacteriophage numbers and to measure the average bacterial volume and velocity, to make predictions about the number of bacteriophages adsorbed on their host bacterial by time. The model was validated by experimental measurements in vitro, showing significant goodness of fit when compared the curves. This model was generated as an estimator for effectiveness of inoculation in phage therapy in aquaculture and opens to a wide range of potential applications.