AUTHOR=Felipe de Lima Andreata Matheus , Mian Silas , Andrade Galdino , de Freitas Bueno Adeney , Ventura Mauricio Ursi , Marcondes de Almeida José Eduardo , Fonseca Ivan Eduardo Augusto , Mosela Mirela , Simionato Ane Stéfano , Robaina Renata Rodrigues , Gonçalves Leandro Simões Azeredo TITLE=The current increase and future perspectives of the microbial pesticides market in agriculture: the Brazilian example JOURNAL=Frontiers in Microbiology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1574269 DOI=10.3389/fmicb.2025.1574269 ISSN=1664-302X ABSTRACT=The Brazilian agricultural sector contributes 25% to the national gross domestic product (GDP) and accounts for 49% of the country’s exports, faces significant challenges associated with tropical agriculture. Pests and diseases are major issues that compromise the productivity of various crops. In response, microbial pesticides have increasingly been incorporated as a component of integrated pest and disease management (IPM and IDM, respectively). This study presents a comprehensive analysis of the Brazilian biopesticide market, focusing on bioinsecticides, bionematicides, and biofungicides. Microbial agents, such as Bacillus spp., Trichoderma spp., and Beauveria spp., play a important role in IPM and IDM strategies, acting through multiple biocontrol mechanisms. The biopesticide market in Brazil has grown rapidly, driven by increased adoption by farmers and recent regulatory advances that have facilitated these products’ registration and commercialization process. Projections indicate that this sector will continue to grow in the coming years, supported by research innovations, consolidating biopesticides as key elements in Brazil’s transition to more sustainable agriculture. This review explores the challenges, opportunities, and future trends of microbial pesticides in Brazilian agriculture, highlighting their potential in increasing crop resilience and productivity while reducing the environmental impact associated with conventional pesticides.