ORIGINAL RESEARCH article

Front. Microbiol.

Sec. Food Microbiology

Microbial Diversity of Camel Milk Production Environments in Xinjiang, China: A Full-Length 16S rRNA Survey of Farm Environmental Matrices Across Altay and Hami Regions

  • 1. Ministry of Agriculture and Rural Affairs-Laboratory of Quality and Safety Risk Assessment for Agro-Products, Agricultural Product Quality and Safety Risk Assessment Laboratory, Institute of Quality Standards & Testing Technology for Agro-Products, Xinjiang Academy of Agricultural Sciences, Xinjiang Academy of Agricultural Sciences, Urumqi, China

  • 2. Xinjiang Academy of Agricultural Sciences, Urumqi, China

  • 3. Chinese Academy of Agricultural Sciences, Beijing, China

  • 4. Xinjiang Agricultural University, Ürümqi, China

The final, formatted version of the article will be published soon.

Abstract

This study employed PacBio Single-Molecule Real-Time(SMRT) full-length 16S rRNA gene 17 sequencing to characterize the microbial community structure of production-associated environments 18 across five key environmental matrices (bedding, feces, teat skin, feed, and soil) in camel breeding farms in the Altay and Hami regions of Xinjiang, China. The dominant phyla in the filtered environmental microbiome (post-removal of chloroplast and mitochondrial sequences) were Firmicutes (43.20%), Proteobacteria (20.12%), and Actinobacteriota (12.02%), calculated from pooled read counts across all samples. Alpha diversity analysis revealed significantly higher richness of fecal and feed microbial communities in Altay compared to Hami (Padj < 0.05), while beta diversity analyses (PCoA, NMDS, PERMANOVA) confirmed distinct taxonomic profiles between the two regions, driven by both regional and sample-type effects. Functional profiling based on the COG database indicated conserved metabolic potentials across regions, with enrichment of pathways related to amino acid transport and energy conversion. This work provides a foundational baseline of camel farm environmental microbiomes, informing targeted hygiene interventions and future studies linking environmental reservoirs to raw milk quality. A core limitation is the absence of raw milk samples, precluding direct inference of microbial transmission routes to milk.

Summary

Keywords

Microbial Diversity, production environment, Raw camel milk, single-molecule real-time sequencing, source tracking

Received

14 July 2026

Accepted

17 August 2026

Copyright

© 2026 Wu, Wang, Ma, Lou, Zheng, Shao, Meng, Chen, Cheng and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Wang Cheng; Yankun Zhao

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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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