AUTHOR=Navalkele Bhagyashri D. , Chopra Teena 

TITLE=Clinical application of live biotherapeutic products in infectious diseases

JOURNAL=Frontiers in Microbiomes

VOLUME=Volume 3 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/microbiomes/articles/10.3389/frmbi.2024.1415083

DOI=10.3389/frmbi.2024.1415083

ISSN=2813-4338

ABSTRACT=Live biotherapeutics products (LBP) are a novel range of therapeutic options in medicine. In this review, authors discuss basic composition and mechanism of action of LBP, provide a comprehensive focused overview of published in vitro and in vivo studies on efficacy of LBP for prevention and treatment of infectious diseases such as viral (HIV, COVID-19), bacterial (C.difficile infection, bacterial vaginosis, multi-drug resistant organisms) and fungal (Candida) organisms. This review should be of interest to clinicians to understand the broad application of LBP in infectious diseases world beyond recurrent C.difficile infection and to researchers on unexplored prospects of LBP and the need for further investigation in this emerging field to improve its clinical application.