AUTHOR=Meng Qingkun , Tan Hao , Wang Chengfu , Sun Zhijun 

TITLE=Progress and trends in myocardial infarction-related long non-coding RNAs: a bibliometric analysis

JOURNAL=Frontiers in Molecular Biosciences

VOLUME=Volume 11 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2024.1382772

DOI=10.3389/fmolb.2024.1382772

ISSN=2296-889X

ABSTRACT=Myocardial infarction (MI), a critical condition, substantially affects patient outcomes and mortality rates. Long non-coding RNAs (lncRNAs) play a critical role in the onset and progression of MI. This study aimed to explore the related research on MI-related lncRNAs from a bibliometric perspective.A comprehensive search was conducted on August 7, 2023, using the Web of Science Core Collection (WoSCC) database to compile a dataset of all English-language scientific journals. The search gathered all relevant publications from January 2000 to August 2023. Data on countries, institutions, journals, authors, and keywords were collected, sorted, statistically analyzed, and visualized using CiteSpace 6.2.R4, VOSviewer 1.6.19, an online bibliometric analysis platform (http://bibliometric.com), and the bibliometric package in R-Studio 4.3.1. Articles were screened by two independent reviewers.Between January 2000 and August 2023, a total of 1452 papers were published in the research field. The year with the most publications was 2020, accounting for 256 papers. The publication volume displayed an exponential growth trend. In this domain, China leads in both the number of published papers and total citations, followed by the United States, Germany, Iran, and Italy. The most productive institution is Harbin Medical University (N=144). The European Review for Medical and Pharmacological Sciences had the highest number of publications (N=46), while Circulation Research had the most citations (TC=4537). Research mainly focuses on the cardiovascular system, cellular biology, physiology, etc. The most productive author is Zhang Y. Apart from "Myocardial Infarction" and "LncRNA," the most frequent keywords include "expression," "atherosclerosis," and "apoptosis." Cluster analysis suggests current research themes concentrate on cardiovascular diseases and gene expression, cardiac ischemia/reperfusion injury and protection, expression and proliferation, atherosclerosis and inflammatory response, among others. Keyword bursts indicate recent hot topics as targeting, autophagy, etc.This bibliometric analysis reveals that research on MI-related lncRNAs has rapidly expanded between January 2000 and August 2023, primarily led by China and the United States. Our study provides insights into the features and quality of related publications, as well as the future directions in this research field. There is a long road ahead, highlighting the urgent need for enhanced global academic exchange.