Frontiers in Molecular Biosciences

Original Research

Published on 06 Jul 2023

Automated identification of chalcogen bonds in AlphaFold protein structure database files: is it possible?

in Structural Biology

Oliviero Carugo
Kristina Djinović-Carugo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1155629

4,517 views
6 citations

Original Research

Published on 05 Jul 2023

Understanding structure-guided variant effect predictions using 3D convolutional neural networks

in Structural Biology

Gayatri Ramakrishnan
Coos Baakman
Stephan Heijl
Bas Vroling
Ragna van Horck
Jeffrey Hiraki
Li C. Xue
Martijn A. Huynen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1204157

5,204 views
12 citations

Review

Published on 29 Jun 2023

Dynamic allostery in thrombin—a review

in Structural Biology

Elizabeth A. Komives

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1200465

4,529 views
8 citations

Opinion

Published on 22 Jun 2023

AI-based protein models enhance the accuracy of experimentally determined protein crystal structures

in Structural Biology

Ki Hyun Nam

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1208810

3,979 views
5 citations

Review

Published on 16 Jun 2023

The cytosolic N-terminal domain of V-ATPase a-subunits is a regulatory hub targeted by multiple signals

in Structural Biology

Farzana Tuli
Patricia M. Kane

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1168680

6,812 views
7 citations

Original Research

Published on 09 Jun 2023

Physical pictures of rotation mechanisms of F1- and V1-ATPases: Leading roles of translational, configurational entropy of water

in Structural Biology

Satoshi Yasuda
Tomohiko Hayashi
Takeshi Murata
Masahiro Kinoshita

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1159603

4,061 views
4 citations

Mini Review

Published on 09 May 2023

Reversible binding of divalent cations to Ductin protein assemblies—A putative new regulatory mechanism of membrane traffic processes

in Structural Biology

Krisztina Sebők-Nagy
András Blastyák
Gábor Juhász
Tibor Páli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1195010

2,630 views
3 citations

Original Research

Published on 02 May 2023

Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity

in Structural Biology

Mariano Genera
Baptiste Colcombet-Cazenave
Anastasia Croitoru
Bertrand Raynal
Ariel Mechaly
Joël Caillet
Ahmed Haouz
Nicolas Wolff
Célia Caillet-Saguy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1192621

4,241 views
3 citations

Editorial

Published on 02 May 2023

Editorial: “Small molecules targeting transmembrane receptors and ion channels in drug discovery”

in Structural Biology

Rosa Maria Vitale
Fabio Arturo Iannotti
Tullio Florio

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1183713

2,464 views
1 citation

Original Research

Published on 02 May 2023

Arginine anchor points govern H3 tail dynamics

in Structural Biology

Christine E. Jennings
Casey J. Zoss
Emma A. Morrison

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1150400

4,531 views
12 citations

Review

Published on 24 Apr 2023

Rotary mechanism of V/A-ATPases—how is ATP hydrolysis converted into a mechanical step rotation in rotary ATPases?

in Structural Biology

Ken Yokoyama

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1176114

6,217 views
4 citations

Editorial

Published on 18 Apr 2023

Editorial: In celebration of women in science: Structural biology

in Structural Biology

Roberta Spadaccini

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1174561

1,905 views

Review

Published on 14 Apr 2023

Sweetening K-channels: what sugar taught us about permeation and gating

in Structural Biology

David Naranjo
Ignacio Diaz-Franulic

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1063796

3,127 views
3 citations

Original Research

Published on 07 Apr 2023

V-ATPase modulates exocytosis in neuroendocrine cells through the activation of the ARNO-Arf6-PLD pathway and the synthesis of phosphatidic acid

in Structural Biology

Qili Wang
Alexander Wolf
Sebahat Ozkan
Ludovic Richert
Yves Mely
Sylvette Chasserot-Golaz
Stéphane Ory
Stéphane Gasman
Nicolas Vitale

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1163545

3,565 views
8 citations

Original Research

Published on 30 Mar 2023

The EJC disassembly factor PYM is an intrinsically disordered protein and forms a fuzzy complex with RNA

in Structural Biology

Deepshikha Verma
Veena Hegde
John Kirkpatrick
Teresa Carlomagno

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1148653

3,471 views
3 citations

Original Research

Published on 29 Mar 2023

DNA accelerates the protease inhibition of a bacterial serpin chloropin

in Structural Biology

Jiawei Xu
Wei Ye
Ting Ting Yang
Teng Yan
Haiyan Cai
Aiwu Zhou
Yufeng Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1157186

3,625 views
1 citation

Original Research

Published on 29 Mar 2023

Structural polymorphism of the low-complexity C-terminal domain of TDP-43 amyloid aggregates revealed by solid-state NMR

in Structural Biology

Jayakrishna Shenoy
Alons Lends
Mélanie Berbon
Muhammed Bilal
Nadia El Mammeri
Mathilde Bertoni
Ahmad Saad
Estelle Morvan
Axelle Grélard
Sophie Lecomte

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1148302

5,847 views
17 citations

Original Research

Published on 28 Mar 2023

Riboflavin kinase and pyridoxine 5′-phosphate oxidase complex formation envisages transient interactions for FMN cofactor delivery

in Structural Biology

Maribel Rivero
Sergio Boneta
Nerea Novo
Adrián Velázquez-Campoy
Victor Polo
Milagros Medina

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1167348

5,155 views
7 citations

Original Research

Published on 16 Mar 2023

Structural and oxidative investigation of a recombinant high-yielding fetal hemoglobin mutant

in Structural Biology

Karin Kettisen
Maria Nyblom
Emanuel Smeds
Angela Fago
Leif Bülow

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1133985

7,624 views
3 citations

Original Research

Published on 16 Mar 2023

Mobile genetic element-encoded putative DNA primases composed of A-family polymerase—SSB pairs

in Structural Biology

Phoebe A. Rice

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1113960

2,612 views

Editorial

Published on 15 Mar 2023

Editorial: Structural biology of nucleic acid replication, recombination and repair

in Structural Biology

Edward L. Bolt
Christopher D. O. Cooper
Nicholas P. Robinson

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1155089

2,409 views

Editorial

Published on 09 Mar 2023

Editorial: Antiviral drug discovery against pathogens of pandemic concern: Advancements in target site identification and structure-based drug development

in Structural Biology

Krishna M. Padmanabha Das

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165208

4,084 views
1 citation

Methods

Published on 07 Mar 2023

A simple flash and freeze system for cryogenic time-resolved electron microscopy

in Structural Biology

Biddut Bhattacharjee
Md Mahfuzur Rahman
Ryan E. Hibbs
Michael H. B. Stowell

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1129225

6,101 views
10 citations

Original Research

Published on 02 Mar 2023

Enhancing response of a protein conformational switch by using two disordered ligand binding domains

in Structural Biology

Harsimranjit Sekhon
Jeung-Hoi Ha
Stewart N. Loh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1114756

4,379 views
9 citations

496 articles

articles

Automated identification of chalcogen bonds in AlphaFold protein structure database files: is it possible?

Understanding structure-guided variant effect predictions using 3D convolutional neural networks

Dynamic allostery in thrombin—a review

AI-based protein models enhance the accuracy of experimentally determined protein crystal structures

The cytosolic N-terminal domain of V-ATPase a-subunits is a regulatory hub targeted by multiple signals

Physical pictures of rotation mechanisms of F1- and V1-ATPases: Leading roles of translational, configurational entropy of water

Reversible binding of divalent cations to Ductin protein assemblies—A putative new regulatory mechanism of membrane traffic processes

Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity

Editorial: “Small molecules targeting transmembrane receptors and ion channels in drug discovery”

Arginine anchor points govern H3 tail dynamics

Rotary mechanism of V/A-ATPases—how is ATP hydrolysis converted into a mechanical step rotation in rotary ATPases?

Editorial: In celebration of women in science: Structural biology

Sweetening K-channels: what sugar taught us about permeation and gating

V-ATPase modulates exocytosis in neuroendocrine cells through the activation of the ARNO-Arf6-PLD pathway and the synthesis of phosphatidic acid

The EJC disassembly factor PYM is an intrinsically disordered protein and forms a fuzzy complex with RNA

DNA accelerates the protease inhibition of a bacterial serpin chloropin

Structural polymorphism of the low-complexity C-terminal domain of TDP-43 amyloid aggregates revealed by solid-state NMR

Riboflavin kinase and pyridoxine 5′-phosphate oxidase complex formation envisages transient interactions for FMN cofactor delivery

Structural and oxidative investigation of a recombinant high-yielding fetal hemoglobin mutant

Mobile genetic element-encoded putative DNA primases composed of A-family polymerase—SSB pairs

Editorial: Structural biology of nucleic acid replication, recombination and repair

Editorial: Antiviral drug discovery against pathogens of pandemic concern: Advancements in target site identification and structure-based drug development

A simple flash and freeze system for cryogenic time-resolved electron microscopy

Enhancing response of a protein conformational switch by using two disordered ligand binding domains