AUTHOR=Wang Ming , Chen Yinghui 

TITLE=Inflammation: A Network in the Pathogenesis of Status Epilepticus

JOURNAL=Frontiers in Molecular Neuroscience

VOLUME=Volume 11 - 2018

YEAR=2018

URL=https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2018.00341

DOI=10.3389/fnmol.2018.00341

ISSN=1662-5099

ABSTRACT=Status epilepticus (SE) is an abnormally prolonged or recurrent epileptic seizure that is a serious, life-threatening medical emergency. Notably, it requires prompt, aggressive treatment. SE is characterized by high mortality and morbidity. However, its pathogenesis remains unclear. Numerous studies of SE have reported widespread brain inflammation, suggesting that inflammation plays a vital role in the occurrence and development of SE. This article reviews current knowledge regarding the role of inflammation in SE.