AUTHOR=Alvarez Beatriz , Symmank Judit , Zimmer-Bensch Geraldine , Diaz-Hernandez Miguel , Franzka Patricia TITLE=Editorial: Protein post-translational modifications in the nervous system: from development to disease and ageing JOURNAL=Frontiers in Molecular Neuroscience VOLUME=Volume 17 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2024.1501719 DOI=10.3389/fnmol.2024.1501719 ISSN=1662-5099 ABSTRACT=Graphical AbstractPTMs are crucial for biological processes contributing to healthy organ function. Protein post-translational modifications (PTMs), such as phosphorylation (P), acetylation (Ac), SUMOylation (SUMO), S-nitrosylation (Nitro), ubiquitination (Ub) and glycosylation (Glyco), affect a wide range of cellular and biological functions as depicted in this cartoon. Perturbations lead to severe consequences for the normal function of the brain and other organs, such as muscle. Created in BioRender. Hübner (2024) BioRender.com/j49w898.