AUTHOR=Lei Sean , Shankar Abhirami , Sethi Supreet , Lum Erik L. 

TITLE=Kidney transplantation between identical twins with APOL1 homozygote risk alleles – a case report

JOURNAL=Frontiers in Nephrology

VOLUME=Volume 5 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/nephrology/articles/10.3389/fneph.2025.1648263

DOI=10.3389/fneph.2025.1648263

ISSN=2813-0626

ABSTRACT=Kidney transplantation is the optimal therapy for individuals with end-stage kidney disease. Recent studies suggest a negative impact of high-risk Apolipoprotein L1 genotypes on outcomes for both living kidney donors and kidney transplant recipients. In this case, we describe a pair of identical twins with a high-risk APOL1 genotype who underwent successful living kidney transplantation with excellent short-term outcomes.