AUTHOR=Costa Frederico P. , Tuszynski Jack , Iemma Antonio F. , Trevizan Willian A. , Wiedenmann Bertram , Schöll Eckehard TITLE=External low energy electromagnetic fields affect heart dynamics: surrogate for system synchronization, chaos control and cancer patient’s health JOURNAL=Frontiers in Network Physiology VOLUME=Volume 4 - 2024 YEAR=2025 URL=https://www.frontiersin.org/journals/network-physiology/articles/10.3389/fnetp.2024.1525135 DOI=10.3389/fnetp.2024.1525135 ISSN=2674-0109 ABSTRACT=All cells in the human body, including cancer cells, possess specific electrical properties crucial for their functions. These properties are notably different between normal and cancerous cells. Cancer cells are characterized by autonomous oscillations and damped electromagnetic field (EMF) activation. Cancer reduces physiological variability, implying a systemic disconnection that desynchronizes bodily systems and their inherent random processes. The dynamics of heart rate, in this context, could reflect global physiological network instability in the sense of entrainment. Using a medical device that employs an active closed-loop system, such as administering specifically modulated EMF frequencies at targeted intervals and at low energies, we can evaluate the periodic oscillations of the heart. This procedure serves as a closed-loop control mechanism leading to a temporary alteration in plasma membrane ionic flow and the heart’s periodic oscillation dynamics. The understanding of this phenomenon is supported by computer simulations of a mathematical model, which are validated by experimental data. Heart dynamics can be quantified using difference logistic equations, and it correlates with improved overall survival rates in cancer patients.