AUTHOR=Lehmann Alexander , D’Errico Anna , Vogel Martin , Spors Hartwig TITLE=Spatio-Temporal Characteristics of Inhibition Mapped by Optical Stimulation in Mouse Olfactory Bulb JOURNAL=Frontiers in Neural Circuits VOLUME=Volume 10 - 2016 YEAR=2016 URL=https://www.frontiersin.org/journals/neural-circuits/articles/10.3389/fncir.2016.00015 DOI=10.3389/fncir.2016.00015 ISSN=1662-5110 ABSTRACT=
Mitral and tufted cells (MTCs) of the mammalian olfactory bulb are connected via dendrodendritic synapses with inhibitory interneurons in the external plexiform layer. The range, spatial layout, and temporal properties of inhibitory interactions between MTCs mediated by inhibitory interneurons remain unclear. Therefore, we tested for inhibitory interactions using an optogenetic approach. We optically stimulated MTCs expressing channelrhodopsin-2 in transgenic mice, while recording from individual MTCs in juxtacellular or whole-cell configuration