AUTHOR=Diarra Moussa , Theurel Jean , Paty Benjamin TITLE=Systematic review of neurophysiological assessment techniques and metrics for mental workload evaluation in real-world settings JOURNAL=Frontiers in Neuroergonomics VOLUME=Volume 6 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/neuroergonomics/articles/10.3389/fnrgo.2025.1584736 DOI=10.3389/fnrgo.2025.1584736 ISSN=2673-6195 ABSTRACT=IntroductionMental Workload (MWL) is a concept that has garnered increasing interest in professional settings but remains challenging to define consensually. The literature reports a plurality of operational definitions and assessment methods, with no established unified framework. This review aims to identify objective and validated measurement methods for evaluating MWL in real-world work contexts. Particular attention is given to neurophysiological methods, recognized for their efficiency and robustness, enabling real-time assessment without disrupting operator activity.MethodTo conduct this analysis, a systematic search was performed in three databases (PubMed, ScienceDirect, and IEEEXplore), covering studies published from their inception until March 30, 2023. Selection criteria included research focusing on MWL and its derivatives, as well as neurophysiological measures applied in real-world conditions. An initial screening based on titles and abstracts was followed by an in-depth review, assisted by the bibliometric software Rayyan.ResultsThe explored concepts, applied methods, and study results were compiled into a synthesis table. Ultimately, 35 studies were included, highlighting the diversity of measurement tools used in field settings, often combined with subjective assessments.DiscussionFurthermore, key physiological indicators such as ECG, eye data, EEG and the relationship between MWL metrics and those uses to measure stress are emphasized and discussed. A better understanding of these interrelations could refine the assessment of their respective impacts and help anticipate their consequences on workers' mental health and safety.