AUTHOR=Sveinsson Olafur TITLE=A Striking Response to Lithium in Kleine–Levin Syndrome JOURNAL=Frontiers in Neurology VOLUME=Volume 5 - 2014 YEAR=2014 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2014.00033 DOI=10.3389/fneur.2014.00033 ISSN=1664-2295 ABSTRACT=Kleine-Levin syndrome (KLS) is an episodic hypersomnia with cognitive disturbances such as confusion, apathy and derealisation. Hyperphagia and hyper sexuality occur in around 50% of cases. No evidence-based treatments have been established for Kleine Levin syndrome. Many drugs have been tried, most often with little success. Here a case with a striking response to lithium is presented.