AUTHOR=Wang Ming , Gu Jun , Lan Ping , Wan Shu , Zhou Yongqing , Zheng Xiujue , Zhan Renya TITLE=A Persistent Primitive Hypoglossal Artery As the Sole Supply to the Brain Associated with a Basilar Bifurcation Aneurysm JOURNAL=Frontiers in Neurology VOLUME=Volume 8 - 2017 YEAR=2017 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00168 DOI=10.3389/fneur.2017.00168 ISSN=1664-2295 ABSTRACT=The persistent primitive hypoglossal artery (PPHA) is the second most common persistent carotid-vertebrobasilar anastomosis, with an incidence of 0.027-0.26%.PPHAs change the hemodynamics of the carotid and vertebral-basilar system and may be associated with intracranial vascular anomalies, but basilar bifurcation aneurysms were rarely reported. We describe the first case of a PPHA as the sole supply to the brain associated with a basilar bifurcation aneurysm and review the literature. We reported a 34-year-old woman who presented with subarachnoid hemorrhage due to a ruptured basilar bifurcation aneurysm. Digital subtraction arteriogram revealed a right persistent primitive hypoglossal artery as the sole supply to the brain. The aneurysm was successfully clipped under intraoperative neurophysiology.