AUTHOR=Gil-Gouveia Raquel , Pinto Joana , Figueiredo Patricia , Vilela Pedro Ferro , Martins Isabel Pavão 

TITLE=An Arterial Spin Labeling MRI Perfusion Study of Migraine without Aura Attacks

JOURNAL=Frontiers in Neurology

VOLUME=Volume 8 - 2017

YEAR=2017

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00280

DOI=10.3389/fneur.2017.00280

ISSN=1664-2295

ABSTRACT=Background: Studies of brain perfusion during migraine without aura attacks have inconsistent results. 
Methods: Arterial Spin Labeling (ASL) MRI, a non-invasive quantitative perfusion technique, was used to prospectively study a spontaneous untreated migraine without aura attack and a headache-free period. Image analysis used FSL and MATLAB software; Group analysis used permutation methods for perfusion differences between sessions. 
Results: Thirteen women (age 35.7) were scanned during an attack of an average intensity of 6.8 (on 0-10 Visual Analogue Scale, VAS) and 16 hours duration. No global or regional perfusion differences were identified comparing migraine and migraine-free sessions.
Discussion: Our findings suggest that the painful phase of migraine without aura attacks is not associated with brain perfusion abnormalities