AUTHOR=Cui Linyang , Xu Zushan , Hou Hongjun 

TITLE=Diagnosis and Treatment of Spinal Syphilitic Gumma: A Case Report

JOURNAL=Frontiers in Neurology

VOLUME=Volume 10 - 2019

YEAR=2020

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.01352

DOI=10.3389/fneur.2019.01352

ISSN=1664-2295

ABSTRACT=Neurosyphilis is a rare sexually-transmitted disease caused by Treponema pallidum involving the central nervous system (CNS). Spinal syphilitic gumma is extremely rare; only a few cases of spinal syphilitic gumma have been reported in the previous literature and almost all of them are subjected to surgery. Here we report a 46-year-old man, who presented with 5-day bilateral lower-limb numbness and lower back pain. Magnetic resonance imaging (MRI) suggested a homogeneous peripheral enhancement, intramedullary nodule at the T7 level  associated with extensive thoracic cord edema. Laboratory examination and MRI revealed a syphilitic gumma. After penicillin G was used, the symptoms vanished a month latter and his intramedullary nodule disappeared as a result of  the imaging after 6-month.