AUTHOR=Yan Xiuli , Liu Zhuo , Guo Zhen-Ni , Sun Ye , Jin Hang , Sun Xin , Sun Huijie , Yang Yi TITLE=Positive Influence of Stroke Health Manager on Risk Factors Control and Medication Adherence After Ischemic Stroke JOURNAL=Frontiers in Neurology VOLUME=Volume 11 - 2020 YEAR=2020 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2020.00168 DOI=10.3389/fneur.2020.00168 ISSN=1664-2295 ABSTRACT=Abstract Background—From 2017, the Stroke Health Manager Training Project was carried out by the Chinese Government to strengthen health management and follow-up intervention after ischemic stroke. The aim of this study was to investigate whether after the intervention of the stroke health manager, the control of blood pressure, low-density lipoprotein cholesterol (LDL-C), glucose level, and the use of secondary prevention medications improved three months after discharge from our center following ischemic stroke. Methods—The study used a history-controlled approach. Patients who received stroke health manager intervention from May 1, 2018, to March 31, 2019, were considered as the intervention group; those from May 1, 2017, to April 30, 2018, were enrolled as the control group. Stroke health manager intervention included health education, discharge advice, online WeChat public group follow-up, and clinical consultation. Results—In total, 642 patients with ischemic stroke were enrolled in this study (277 in the control group, 365 in the intervention group). At three months, the blood pressure, LDL-C and glucose control in the intervention group were better than in the control group (all P < 0.05). At the same time, the overall persistence for secondary prevention medications at three months after discharge increased from 201/277 (72.56%) to 303/365 (83.01%, P = 0.001). The persistence for patients taking antiplatelet, hypoglycemic and statins were significantly higher in the intervention group (P < 0.05). Conclusions—Stroke health manager intervention improved the control of blood pressure, LDL-C, glucose levels and the persistence for secondary prevention medications three months after discharge.