AUTHOR=Cheng Hongjiang , Yang Fengbing , Zhang Jing , Xu Lina , Jia Longbin , Zhao Doudou , Liu Wei , Li Huimin 

TITLE=Case Report: Anti-NMDA Receptor Encephalitis With Bilateral Hearing Loss as the Initial Symptom

JOURNAL=Frontiers in Neurology

VOLUME=Volume 12 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2021.648911

DOI=10.3389/fneur.2021.648911

ISSN=1664-2295

ABSTRACT=Introduction: Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune disease associated with the NMDA receptor. This paper describes a patient who presented with bilateral hearing loss as the initial symptom of anti-NMDAR encephalitis.
Case Report: we describe a 31-year-old young female with anti-NMDAR encephalitis who presented with complete bilateral hearing loss after brief loss of consciousness,then accompanied with other symptoms,such as generalized tonic-clonic seizures,manic episodes,excessive salivation,severe cognitive impairment and complex nonconvulsive status epilepticus.Great improvement was achieved by a combined treatment of steroid,IVIG and plasmapheresis,especially after surgical removal of ovarian teratoma.When she was discharged on hospital day 43, her hearing loss obtained a significant improvement.
Conclusion: This case study and literature review investigated the impairment of
hearing loss and its subsequent treatment in patients with anti-NMDAR encephalitis.