AUTHOR=Wang Zhuo , Zhao Munan , Gao Sujun 

TITLE=Epileptic Seizures After Allogeneic Hematopoietic Stem Cell Transplantation

JOURNAL=Frontiers in Neurology

VOLUME=Volume 12 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2021.675756

DOI=10.3389/fneur.2021.675756

ISSN=1664-2295

ABSTRACT=Technique in allogeneic hematopoietic stem cell transplantation has greatly advanced over the past decades, which has led to an increase in the number of patients receiving transplantation, but the complex procedures place these transplant recipients at highrisk for a large spectrum of complications including neurologic involvement. As a common manifestation of neurological disorders, epileptic seizures after transplantation have been of great concern to clinicians because it seriously affects the survival rate and quality of life of those recipients. The aim of this review is to elucidate the incidence of seizures after allogeneic hematopoietic stem cell transplantation, and to further detailedly summarize its etiologies, possible mechanisms, clinical manifestations, therapeutic schedule and prognosis, hoping to improve doctors’ understandings of concurrent seizures following transplantation, so they can prevent earlier, process timely and correctly, eventually improving the survival and outlook for patients.