AUTHOR=Akram Muhammad Junaid , Zhao Rui , Shen Xue , Yang Wen-Song , Deng Lan , Li Zuo-Qiao , Hu Xiao , Zhao Li-Bo , Xie Peng , Li Qi 

TITLE=Surgical vs. Conservative Management for Lobar Intracerebral Hemorrhage, a Meta-Analysis of Randomized Controlled Trials

JOURNAL=Frontiers in Neurology

VOLUME=Volume 12 - 2021

YEAR=2022

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2021.742959

DOI=10.3389/fneur.2021.742959

ISSN=1664-2295

ABSTRACT=Background: Outcomes regarding the conventional surgical and conservative treatment for the lobar intracerebral hemorrhage have not been compared previously. The current meta-analysis was designed to review and compile the evidence regarding the management of patients with lobar intracerebral hemorrhage.
Methods: Online electronic databases including PubMed, Embase, Medline, Cochrane Library and Google Scholar were searched for randomized controlled trials. Studies were selected on the basis of the inclusion and exclusion criteria. Trials with computerized tomography-confirmed lobar intracerebral hemorrhage patients of which treatment regimen was started within 72 hours following the stroke were included. Low quality trials were excluded. Death or the dependence was defined as primary outcome and death at the end of the follow up was the secondary outcome.  
Results: 105 randomized controlled trials were screened, 96 articles were excluded on the basis of abstract. 9 articles were assessed for the eligibility and 7 trials were included involving 1102 patients. The OR for the primary outcome was 0.80 (95% CI, 0.62-1.04, P=0.09) and for the secondary outcome was 0.79 (95%CI, 0.60-1.03, P=0.09).
Conclusion: Our findings suggested that surgical treatments did not significantly improve the functional outcome as compared with the conservative medical management for  patients with lobar ICH.