AUTHOR=Zhang Weijun , Lu Hongji , Liu Jia , Ou Aihua , Zhang Pandeng , Zhong Jingxin 

TITLE=The consistency of invasive and non-invasive arterial blood pressure for the assessment of dynamic cerebral autoregulation in NICU patients

JOURNAL=Frontiers in Neurology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.1032353

DOI=10.3389/fneur.2022.1032353

ISSN=1664-2295

ABSTRACT=Background: Studies of the clinical application of dynamic cerebral autoregulation show considerable variations, and differences in blood pressure devices may be one of the reasons for this variation. Few studies have examined the consistency of invasive and noninvasive arterial blood pressure for evaluating cerebral autoregulation. We attempted to investigate the agreement between invasive and noninvasive blood pressure methods in the assessment of dynamic cerebral autoregulation with transfer function analysis.
Methods: Continuous cerebral blood flow velocity and continuous invasive and noninvasive arterial blood pressure were simultaneously recorded for 15 minutes. Transfer function analysis was applied to derive the phase shift, gain and coherence function at all frequency bands from the first 5, 10, and 15 minutes of the 15-minute recordings. The consistency was assessed with Bland–Altman analysis and intraclass correlation coefficient.
Results: The consistency of invasive and noninvasive blood pressure methods for the assessment of dynamic cerebral autoregulation was poor at 5 minutes, slightly improved at 10 minutes, and good at 15 minutes. The values of the phase shift at the low-frequency band measured by the noninvasive device were higher than those measured with invasive equipment. The coherence function values measured by the invasive technique were higher than the values derived from the noninvasive method.
Conclusion: Both invasive and noninvasive arterial blood pressure methods have good agreement in evaluating dynamic cerebral autoregulation when the recording duration reaches 15 minutes. The phase shift values measured with noninvasive techniques are higher than those measured with invasive devices. We recommend selecting the most appropriate blood pressure device to measure cerebral autoregulation based on the disease, purpose, and design.