AUTHOR=Ng Shamay S. M. , Liu Tai-Wa , Tsoh Joshua , Chen Peiming , Cheng Tony S. , Cheung Marco C. H. , Leung Anthony H. H. , Ng Liam L. Y. , So Ken Y. K. , Tse Mimi M. Y. TITLE=Psychometric Properties of the Trail Walking Test for People With Stroke JOURNAL=Frontiers in Neurology VOLUME=Volume 13 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.821670 DOI=10.3389/fneur.2022.821670 ISSN=1664-2295 ABSTRACT=Objective: To investigate (I) the inter-rater and test–retest reliability of the Trail Walking Test (TWT) and the minimum detectable change in the TWT completion time; (ii) the correlations between the TWT completion time and stroke-specific impairments; and (iii) the cutoff TWT completion time to distinguish between people with stroke and healthy older adults according to dual-tasking ambulation ability. Design: Cross-sectional study Setting: University-based rehabilitation center Participants: 104 people with stroke and 53 healthy older adults Main outcome measures: The TWT, the Fugl-Meyer Assessment of Lower Extremity (FMA-LE), the ankle strength test, the Limit of Stability (LOS) test, the Berg Balance Scale (BBS), the Timed Up and Go test (TUG), and the Community Integration Measure (CIM) Results: The mean TWT completion time in subjects with stroke was 124.906 seconds. The TWT demonstrated excellent inter-rater reliability (intra-class correlation [ICC] = 0.999) and good test–retest reliability (ICC = 0.876) in people with stroke. The TWT performance demonstrated significant negative correlations with the FMA-LE scores (r = -0.409), LOS movement velocity (affected and unaffected sides; r = -0.320 and -0.388, respectively), and LOS endpoint excursion (affected and unaffected sides; r = -0.357 and -0.394, respectively); a significant positive correlation with the LOS reaction time (affected side; r = 0.256); a moderate negative correlation with the BBS scores (r = -0.72); and an excellent positive correlation with the TUG completion time (r = 0.944). The receiver operating characteristic curve analysis revealed that an optimal cutoff of 69.61 seconds for the TWT completion time had an outstanding diagnostic power to distinguish between people with stroke and healthy older adults (area under the curve = 0.919) with high sensitivity (88.5%) and specificity (83.0%). Conclusion: Results of our preliminary study demonstrated that the TWT is a reliable, valid, sensitive and specific clinical test for evaluating dual-tasking ambulation ability in people with stroke aged 45 or above and without cognitive impairments. It can differentiate the dual-tasking ambulation ability between people with stroke and healthy older adults.