AUTHOR=Wang Ruideng , Zhou Rubing , Chen Zhengyang , Gao Shan , Zhou Fang TITLE=The Glial Cells Respond to Spinal Cord Injury JOURNAL=Frontiers in Neurology VOLUME=Volume 13 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.844497 DOI=10.3389/fneur.2022.844497 ISSN=1664-2295 ABSTRACT=It's been over 100 years since glial cells were discovered by Virchow. Since then, a great deal of research was carried out to specify these further roles and properties of glial cells in CNS. As it’s well known that glial cells including astrocytes, microglia, OLs and OPCs play an important role in supporting and enabling effective nervous system function in CNS. After SCI, these glial cells play different roles in spinal cord injury and repair. In this review, we will discuss in detail about the role of glial cells in the normal CNS and how they respond to SCI.