AUTHOR=Jin Ji , Guo Geng , Ren Yeqing , Yang Biao , Wu Yongqiang , Wang Shule , Sun Yanqi , Wang Xiaogang , Wang Yuxiao , Zheng Jianzhong 

TITLE=Risk Factors for Recurrence of Intracranial Aneurysm After Coil Embolization: A Meta-Analysis

JOURNAL=Frontiers in Neurology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.869880

DOI=10.3389/fneur.2022.869880

ISSN=1664-2295

ABSTRACT=Intracranial aneurysm is a severe cerebral disorder involving complicated risk factors and endovascular coiling is a common therapeutic selection for intracranial aneurysm. The recurrence is a clinical challenge in intracranial aneurysms after coil embolization. With this study, we provided a meta-analysis of the risk factors for recurrence of intracranial aneurysm after coil embolization. Nine studies were included with a total of 1270 studies were retrieved from the database. The sample size of patients with intracranial aneurysms ranged from 241 to 3530, and a totally 9532 patients were included in the present meta-analysis. The intracranial aneurysms that occurred in middle cerebral artery (MCA) (OR=1.09, 95% CI:1.03-1.16, P=0.0045) and posterior circulation (OR=2.01, 95% CI:1.55-2.60, P=0.000) presented the significantly higher risk of recurrence after coil embolization. Meanwhile, intracranial aneurysms of size > 7 mm (OR=5.38, 95%CI:3.76-7.70, P=0.000) had a significantly higher risk of recurrence after coil embolization. Moreover, ruptured aneurysm (OR=2.86, 95% CI:2.02-4.04, P=0.000) and subarachnoid hemorrhage (SAH) (OR=1.57, 95% CI:1.20-2.06, P=0.001) was positively correlated with the risk of recurrence after coil embolization. In conclusion, this meta-analysis identified the characteristics of intracranial aneurysms with MCA, posterior circulation, size > 7 mm, ruptured aneurysm, and SAH as the risk factors of recurrence after coil embolization for intracranial aneurysms.