AUTHOR=Bastide Laure , Perrotta Gaetano , Lolli Valentina , Mathey Céline , Vierasu Ortensa-Irina , Goldman Serge , Vandergheynst Frédéric 

TITLE=Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report

JOURNAL=Frontiers in Neurology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.995875

DOI=10.3389/fneur.2022.995875

ISSN=1664-2295

ABSTRACT=Background: Only a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign. 

Results: Here we report the first case of central nervous system (CNS) demyelination with systemic inflammatory findings on whole body 19-fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT) following the ChAdOx1 nCoV-19 vaccine. 

Conclusions: Clinicians should stay aware of potential new adverse events after immunization.