AUTHOR=Xu Min , Xue Ya , Chao Xiaofeng , Chen Zhenglou , Wang Yunjiang , Huo Xuqi , Ji Xiang , Wang Hongshen TITLE=Cryptogenic recurrent spontaneous intracranial epidural hematoma: A case report and literature review JOURNAL=Frontiers in Neurology VOLUME=Volume 14 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1123108 DOI=10.3389/fneur.2023.1123108 ISSN=1664-2295 ABSTRACT=Background: Spontaneous epidural hematoma (EDH) has been suggested associated with adjacent infective pathologies, dural vascular malformations, extradural metastasis, or coagulopathies. Cryptogenic spontaneous EDH is extremely rare. Case presentation: We reported a cryptogenic spontaneous EDH case in a young woman following sexual intercourse. She occurred consecutively EDH at three different sites within a short time. After three timely operations, a satisfactory outcome was achieved. Conclusion: EDH should be investigated when a young patient develops headaches and signs of increased ICP after emotional hyperactivity or hyperventilation. If early diagnosis and surgical decompression can be carried out in time, the prognosis is satisfactory.