AUTHOR=Sharma Rohan , Tsikvadze Mariam , Peel Jeffrey , Howard Levi , Kapoor Nidhi , Freeman William D. TITLE=Multimodal monitoring: practical recommendations (dos and don'ts) in challenging situations and uncertainty JOURNAL=Frontiers in Neurology VOLUME=Volume 14 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1135406 DOI=10.3389/fneur.2023.1135406 ISSN=1664-2295 ABSTRACT=With the advancements in modern medicine, new modalities are being developed for monitoring patients in critical care unit. Different modalities evaluate different aspects of patient’s physiology and clinical status. Complexities of said modalities often limit their use to the realm of clinical research, limiting their use in the real world. Understanding the salient features of these modalities and their limitations can aid physicians to interpret the concomitant information provided by multiple modalities to make judicious decisions that may affect clinical care and outcomes. We present a review of the commonly used modalities in the neurological intensive care units with practical recommendations for their use.