AUTHOR=Danielli Ethan , Simard Nicholas , DeMatteo Carol A. , Kumbhare Dinesh , Ulmer Stephan , Noseworthy Michael D. TITLE=A review of brain regions and associated post-concussion symptoms JOURNAL=Frontiers in Neurology VOLUME=Volume 14 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1136367 DOI=10.3389/fneur.2023.1136367 ISSN=1664-2295 ABSTRACT=The human brain is an exceptionally complex organ that is comprised of billions of neurons. Therefore, when a traumatic event such as concussion occurs, somatic, cognitive, behavioral and sleep impairments are the common outcome. Each concussion is unique in the sense that the magnitude of biomechanical forces, and the direction, rotation, and source of those forces, is different for each concussive event. This helps to explain the unpredictable nature of post-concussion symptoms that can arise and resolve. The purpose of this narrative review is to connect the