AUTHOR=Polverino Paola , De Santis Tiziana , Perdixi Elena , Chiò Adriano , Albanese Alberto 

TITLE=Case report: Atypical Parkinsonism following SARS-CoV-2 infection

JOURNAL=Frontiers in Neurology

VOLUME=Volume 14 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1208213

DOI=10.3389/fneur.2023.1208213

ISSN=1664-2295

ABSTRACT=A wide range of neurological manifestations have been reported during Covid-19 pandemic, including a variety of parkinsonian cases. The association of numerous viruses with the development of persistent or transient parkinsonism has been well-documented. We observed a patient who developed a levodopa non-responsive parkinsonian syndrome with dysautonomia during a prolonged stay at home for Covid-19. Although the temporal proximity of the emerging parkinsonian features with a Covid-19 diagnosis suggested a causal relationship, we considered the possibility of a coincidental occurrence of multiple system atrophy. We discuss the patient’s clinical features in relation to established clinical diagnostic criteria and review differential diagnoses as well as the role of SARS-CoV-2 infection.