AUTHOR=Qu Hui-Ling , Sun Xiao-Yu , Dai Ying-Jie 

TITLE=Central pontine myelinolysis: a rare finding in hyperosmolar hyperglycemia

JOURNAL=Frontiers in Neurology

VOLUME=Volume 14 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1216328

DOI=10.3389/fneur.2023.1216328

ISSN=1664-2295

ABSTRACT=Central pontine myelinolysis (CPM) is a heterogeneous nervous system disease of pontine demyelination, usually caused by rapid correction of hyponatremia. Here, we report a unique case of a 46-year-old man with hyperglycemic state complicated with CPM. MRI demonstrated high signal on T2 and symmetric restricted diffusion in the pontine. In conclusion, the clinical case described confirmed that the hyperosmolar state inherent with hyperglycemia was a likely cause of the CPM.