AUTHOR=Chen Yurun , Zhao Pengfei , Ma Xin , Diao Tongxiang , Yu Lisheng 

TITLE=Case report: MRI changes of the inner ear in an MD patient with suspected immune dysfunction

JOURNAL=Frontiers in Neurology

VOLUME=14

YEAR=2023

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1220162

DOI=10.3389/fneur.2023.1220162

ISSN=1664-2295

ABSTRACT=<sec id="sec1"><title>Objectives</title><p>The primary objective of this study was to present the progressive changes from labyrinthitis to endolymphatic hydrops (EH) demonstrated in the inner ear MRI of a patient with MD and suspected immune dysfunction.</p></sec><sec id="sec2"><title>Patient</title><p>This 31-year-old male was diagnosed with MD and suspected autoimmune diseases.</p></sec><sec id="sec3"><title>Interventions</title><p>Immunosuppressants and biological agents.</p></sec><sec id="sec4"><title>Main outcomes measures</title><p>Inner ear MRI images.</p></sec><sec id="sec5"><title>Results</title><p>Changes in the patient’s progress revealed that inner ear immune and inflammatory changes might induce EH, which may eventually turn into MD.</p></sec><sec id="sec6"><title>Conclusion</title><p>This case is the first documented case of MRI revealing progressive changes from inflammatory response to endolymphatic hydrops in the inner ear. It shows the correlation between MD and inflammation visually. It is of great significance to reveal the pathogenesis of MD to further assist in the guidance of treatment decision making.</p></sec>