AUTHOR=Su Yaping , Li Zhenyu , Wang Qian , Tang Hui 

TITLE=Local subcutaneous lidocaine injection for the treatment of complex regional pain syndrome: a case report and literature review

JOURNAL=Frontiers in Neurology

VOLUME=Volume 14 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1232199

DOI=10.3389/fneur.2023.1232199

ISSN=1664-2295

ABSTRACT=A 14-year-old child was diagnosed with complex regional pain syndrome (CRPS) after bromhidrosis surgery. She experienced a prickle-like, knife-like, and intermittent attacks pain, accompanied by numbness of both upper limbs and a limited movement.Ultrasound-guided radiofrequency surgery on peripheral nerve did not reduce pain.Then gabapentin 300mg, three times a day, and 2% lidocaine by local subcutaneous injection, once a day for 3 days, were administrated. After local injection subcutaneous of lidocaine, the pain was significantly relieved and the pain induced by skin touch at the scar disappeared. No pain recurred after 1-month follow-up. An evidence-based literature review showed that local or systemic intravenous lidocaine was used to reduce adult CRPS symptoms, but less has been reported in children. In our case, a local subcutaneous injection of 2% lidocaine in a child for CRPS treatment was reported to be effective in relieving complex local pain with favorable outcomes.Though further high-quality randomized controlled trials are needed to investigate the effects and safety of local subcutaneous lidocaine injection on pain relief in children with CRPS, it could still provide a relatively safe and effective adjuvant therapy for minor patients.