AUTHOR=Yan Lingbo , Liu Chenyu , Zhu Xiaoming , Zhou Dayong , Lv Xiaojiang , Kuang Xuyuan TITLE=Translational medical bioengineering research of traumatic brain injury among Chinese and American pedestrians caused by vehicle collision based on human body finite element modeling JOURNAL=Frontiers in Neurology VOLUME=Volume 14 - 2023 YEAR=2024 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1296902 DOI=10.3389/fneur.2023.1296902 ISSN=1664-2295 ABSTRACT=Based on the size of the Chinese human body and the THUMS AM50 finite element model of the human body, kriging interpolation algorithm was used to model the Chinese 50th percentile human body, and the biological fidelity of the model was verified. Build three different types of passenger vehicle models: sedan, SUV, and MPV, and use mechanical response analysis and finite element simulation to compare and analyze the dynamic differences and head injury differences between the Chinese 50th percentile human body and the THUMS AM50 model during passenger vehicle collisions. The results show that there are obvious differences between the Chinese Mannequin and THUMS in terms of collision time, collision position, invasion speed and angle; When a sedan collides, the skull damage of the Chinese human body is more severe, and when a sedan or SUV collides, the brain damage of the Chinese human body is more severe. The above results suggest that the existing C-NCAP pedestrian protection testing regulations may not provide the best protection for Chinese human bodies, and need to be improved by combining collision damage mechanisms and the physical characteristics of Chinese pedestrians. This thorough investigation is positioned to shed light on the fundamental biomechanics and injury mechanisms at play. Furthermore, the amalgamation of clinically rooted translational and engineering research in the realm of traumatic brain injury has the potential to establish a solid foundation for discerning preventive methodologies. Ultimately, this endeavor holds the potential to introduce effective strategies aimed at preventing and safeguarding against traumatic brain injuries.