AUTHOR=Zhu Haifeng , Deng Zixuan , Xie Yongqi , Qian Guifeng , Wang Danyu , Xie Shaodong , Zhang Yunyi , Yan Peichun 

TITLE=Ultrasound-guided platelet-rich plasma injection for traumatic painful neuroma of brachial plexus: a case report and literature review

JOURNAL=Frontiers in Neurology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1546773

DOI=10.3389/fneur.2025.1546773

ISSN=1664-2295

ABSTRACT=Traumatic neuroma (TN) is a repair response of nerves to direct/indirect trauma or chronic inflammatory injury, commonly occurring after trauma or surgery. The authors report a rare case of a traumatic painful neuroma of the brachial plexus. Physical therapy and drug treatment failed to resolve the symptoms of allodynia and a palpable mass, which significantly reduced the patient’s quality. Ultrasound-guided injection of platelet-rich plasma (PRP) has shown significant efficacy in repairing the nerve and relieving pain. However, there is a lack of research on treating TN with PRP injection. This case demonstrates that ultrasound-guided injection of PRP can alleviate neuropathic pain caused by a traumatic painful neuroma of brachial plexus and improve the upper limb function.