AUTHOR=Kee T. P. , Krings T. , Pace J. , Swaminathan S. K. , Orru' E. TITLE=Ruptured isolated spinal artery aneurysms: a rare manifestation of an arterial dissecting disease JOURNAL=Frontiers in Neurology VOLUME=Volume 16 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1567536 DOI=10.3389/fneur.2025.1567536 ISSN=1664-2295 ABSTRACT=Isolated spinal artery aneurysms (ISAAs) are a rare cause of intracranial and spinal hemorrhages with unclear pathophysiology and natural history and non-standardized management strategies. We hereby present two cases of ruptured ISAAs of posterior spinal arteries treated with open surgery and embolization, respectively. Case presentations are followed by a comprehensive literature review on ISAA pathophysiology, natural history, and management strategies.