AUTHOR=Chapelle Anne-Catherine 

TITLE=Anterograde degeneration along the visual pathway following optic nerve injury: a review

JOURNAL=Frontiers in Neurology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1623798

DOI=10.3389/fneur.2025.1623798

ISSN=1664-2295

ABSTRACT=The aim of this paper is to review anterograde degeneration throughout the anterior visual pathway, particularly in the optic tracts, the lateral geniculate nucleus, the optic radiations and the visual cortex, following optic nerve injury. Both structural and neuroimaging findings are considered in various diseases, such as optic neuritis and glaucoma. Magnetic resonance imaging findings help localize the specific brain regions where these changes can be observed. Furthermore, particular attention is given to the relationship between cortical atrophy and the location of the associated visual field defect.