AUTHOR=De Gobbi Porto Fábio Henrique , Maia da Silva Mari Nilva , Bravo Célia Sarah Gava Jorge , Porto Gislaine Cristina Lopes Machado , de Paula Wesley Américo Bergamin Granado , Fernandes Sérgio José Silva , Otta Gilberto Miyazaki , Plant Gordon 

TITLE=Neuroimaging in posterior cortical atrophy: an integrative review for clinicians and radiologists

JOURNAL=Frontiers in Neurology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2025.1631245

DOI=10.3389/fneur.2025.1631245

ISSN=1664-2295

ABSTRACT=Posterior cortical atrophy (PCA) is most frequently an atypical variant of Alzheimer’s disease that primarily manifests through visual symptoms of cortical origin. This review provides a comprehensive overview of neuroimaging in PCA, addressing key anatomical and clinical aspects as well as characteristic findings across different imaging modalities. It is intended for non-radiologist clinicians and radiologists who may encounter cognitive dysfunction less frequently, aiming to enhance early recognition and accurate interpretation of imaging studies.