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The specialty deals with the basic mechanisms underlying primary and secondary headaches as well as facial pain, their diagnosis and management, as well as their psychological and social impact. The field is currently at the threshold of an explosion in the understanding, diagnosis and treatment of migraine and other headaches. New drugs and scientific breakthroughs are transforming the science and the practice of headache medicine: after the triptan era, specific CGRP-targeting drugs (antagonists and monoclonal antibodies) and selective 5-HT1F agonists are being developed for migraine. New procedures like peripheral and central neuromodulation are being tested and developed for the acute and the preventive treatment of primary headaches.
Concomitant with the development of new treatments is the development of the basic sciences of headache, and the renewed dedication of clinicians to headache treatment and teaching. Neuroimaging allows us to look and to understand more of the brain in pain. Animal models are available to mimic human migraine. Headache research is vast, increasingly interdisciplinary, rapidly expanding, and intellectually challenging. And yet there are still unexplored areas that are likely to contribute greatly to further understand cephalic pain and optimize treatment efficacy like sex-based differences in pain recognition, inflammation and drug response, fluid balance, and blood brain barrier permeability.
The mission of Headache Medicine and Facial Pain is to bring all relevant specialties together on a single platform. We welcome submissions on headache and facial pain in the areas of epidemiology, pathophysiology, genetics and pharmacogenetics, molecular biology, functional and structural neuroimaging, diagnosis, treatment and treatment guidelines, psychology, neuromodulation, and other non-pharmacological therapies.
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PMCID: all published articles receive a PMCID
Headache Medicine and Facial Pain welcomes submissions of the following article types: Brief Research Report, Case Report, Clinical Trial, Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Study Protocol and Systematic Review.
All manuscripts must be submitted directly to the section Headache Medicine and Facial Pain, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
Articles published in the section Headache Medicine and Facial Pain will benefit from the Frontiers impact and tiering system after online publication. Authors of published original research with the highest impact, as judged democratically by the readers, will be invited by the Chief Editor to write a Frontiers Focused Review - a tier-climbing article. This is referred to as "democratic tiering". The author selection is based on article impact analytics of original research published in all Frontiers specialty journals and sections. Focused Reviews are centered on the original discovery, place it into a broader context, and aim to address the wider community across all of Neurology.
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