AUTHOR=Guo Liang 

TITLE=The Pursuit of Chronically Reliable Neural Interfaces: A Materials Perspective

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 10 - 2016

YEAR=2016

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2016.00599

DOI=10.3389/fnins.2016.00599

ISSN=1662-453X

ABSTRACT=Brain-computer interfaces represent one of the most astonishing technologies in our era. However, the grand challenge of chronic instability and limited throughput of the electrode-tissue interface has significantly hindered the further development and ultimate deployment of such exciting technologies. A multidisciplinary research workforce has been called upon to respond to this engineering need. In this paper, I briefly review this multidisciplinary pursuit of chronically reliable neural interfaces from a materials perspective by analyzing the problem, abstracting the engineering principles, and summarizing the corresponding engineering strategies. I further draw my future perspectives by extending the proposed engineering principles.