AUTHOR=Chowdhury Tumul , Wilkinson Marshall , Cappellani Ronald B. 

TITLE=Hemodynamic Perturbations in Deep Brain Stimulation Surgery: First Detailed Description

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 11 - 2017

YEAR=2017

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2017.00477

DOI=10.3389/fnins.2017.00477

ISSN=1662-453X

ABSTRACT=Background
Hemodynamic perturbations can be anticipated in deep brain stimulation (DBS) surgery and may be attributed to multiple factors. Acute changes in hemodynamics may produce rare but severe complications such as intracranial bleeding, transient ischemic stroke and myocardium infarction. Therefore, this retrospective study attempts to determine the incidence of hemodynamic perturbances (rate) and related risk factors in patients undergoing deep brain stimulation surgery.
Material and Methods
After institutional approval, all patients undergoing DBS surgery for the past ten years were recruited for this study. Demographic characteristics, procedural characteristics and intraoperative hemodynamic changes were noted. Event rate was calculated and the effect of all the variables on hemodynamic perturbations was analyzed by regression model. 
Results
Total hemodynamic adverse events during DBS surgery was 10.8 (0-42) and treated in 57 % of cases. 
Conclusion
Among all the perioperative variables, the baseline blood pressure including systolic, diastolic and mean arterial pressure was found to have highly significant effect on these intraoperative hemodynamic perturbations.