AUTHOR=Pingue Valeria , Gentili Marta , Losurdo Anna , Clementi Emilio , Nardone Antonio 

TITLE=Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 14 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2020.00070

DOI=10.3389/fnins.2020.00070

ISSN=1662-453X

ABSTRACT=Severe spasticity is a frequent and disabling complication in patients presenting disorders of consciousness that hinders their rehabilitative process, and is strongly correlated with pain reducing patients’ quality of life. Here we present the case of a 52-year-old man in an unresponsive wakefulness syndrome following a hypoxic–ischemic encephalopathy who showed improvement of spasticity following intake of levetiracetam.