AUTHOR=Pan Pengjie , Xu Li , Zhang Hongrong , Liu Yuan , Lu Xiaocheng , Chen Gang , Tang Hailiang , Wu Jiang 

TITLE=A Review of Hematoma Components Clearance Mechanism After Subarachnoid Hemorrhage

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 14 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2020.00685

DOI=10.3389/fnins.2020.00685

ISSN=1662-453X

ABSTRACT=Subarachnoid hemorrhage (SAH) is a complicated clinical syndrome, caused by several kinds of cerebrovascular disease, with high morbidity, disability and mortality rate. In recent years, several studies have shown that early brain injury (EBI) is an important factor leading to the poor prognosis of SAH. A major cause of EBI has been attributed that hematoma components invade into the brain parenchyma, resulting in neuronal cell death. Therefore, the clearance of hematoma components is essential in the clinical outcome of patients after SAH. Here, in this review, we provide a summary of the current known hematoma component clearance mechanisms and simultaneously propose a new hypothesis for hematoma component clearance.