AUTHOR=Ezeokafor Ifeoma , Upadhya Archana , Shetty Saritha 

TITLE=Neurosensory Prosthetics: An Integral Neuromodulation Part of Bioelectronic Device

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 15 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2021.671767

DOI=10.3389/fnins.2021.671767

ISSN=1662-453X

ABSTRACT=Bioelectronic medicines (BEMs) constitute a branch of bioelectronic devices (BEDs), are a class of therapeutics that combine neuroscience with molecular biology, immunology, and engineering technologies. Thus, BEMs are the culmination of the thought processes of scientists of varied fields and herald a new era in the treatment of chronic diseases. BEMs work on the principle of neuromodulation of nerve stimulation. Examples of BEMs based on neuromodulation are those which modify neural circuits through deep brain stimulation, vagal nerve stimulation, spinal nerve stimulation, retinal and auditory implants. BEDs may also serve as diagnostic tools by mimicking human sensory systems. Two examples of in-vitro BEDs used as diagnostic agents in biomedical applications based on in-vivo neuro-sensory circuits, are the bioelectronic nose and bioelectronic tongue. The review discusses the ever-growing applications of BEDs to a wide variety of health conditions and practices to improve quality of life.