AUTHOR=Yang Liuqing , Huang Yuzhao , Ma Jiahui , Li Zhenxing , Han Rui , Guo Gangwen , Ni Yuncheng , Hu Rong , Yan Xuebin , Zhou Haocheng , Huang Dong TITLE=Clinical Outcome of Pulsed-Radiofrequency Combined With Transforaminal Epidural Steroid Injection for Lumbosacral Radicular Pain Caused by Distinct Etiology JOURNAL=Frontiers in Neuroscience VOLUME=Volume 15 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2021.683298 DOI=10.3389/fnins.2021.683298 ISSN=1662-453X ABSTRACT=Background: Lumbosacral radicular pain (LSRP) can be caused by disc herniation, spinal stenosis, and failed back surgery syndrome. The clinical effect of pulsed-radiofrequency (PRF) combined with transforaminal epidural steroid injection (TESI) for radiating pain in different population remains unclear. Methods: We retrospectively reviewed the medical recordings of patients with LSRP caused by different etiologies, who underwent PRF and TESI treatment. The primary clinical outcome was assessed by a 10-point Visual Analogue Scale (VAS) pre- and post-treatment. Results: A total of 34 LSRP patients were identified and classified into 3 subgroups (disc herniation, spinal stenosis, and failed back surgery syndrome). The overall immediate pain reduction was 4.4 ± 1.1 after procedure. After a median follow-up of 9.5 months, the VAS decreased from 6.5 ± 1.0 to 2.4 ± 1.9 at the last follow-up. Conclusion: PRF combined with TESI is an effective approach to treat persistent LSRP in distinct population.