AUTHOR=Chopin Adrien , Silver Michael A. , Sheynin Yasha , Ding Jian , Levi Dennis Michael TITLE=Transfer of Perceptual Learning From Local Stereopsis to Global Stereopsis in Adults With Amblyopia: A Preliminary Study JOURNAL=Frontiers in Neuroscience VOLUME=Volume 15 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2021.719120 DOI=10.3389/fnins.2021.719120 ISSN=1662-453X ABSTRACT=It has long been debated whether the analysis of global and local stereoscopic depth is performed by one or separate systems. Global stereopsis requires the visual system to solve a complex binocular matching problem to obtain a coherent percept of depth. In contrast, local stereopsis requires only a simple matching of similar image features. In this case series, we recruited 5 adults with amblyopia who lacked global stereopsis and trained them on a computerized local-disparity stereoscopic depth task for an average of 12 hours. Three out of five (60%) participants recovered fine global stereoscopic vision. Those who recovered tended to start the training with better initial performance on the local-disparity task, to have less severe amblyopia, and to improve more on the local-disparity training task. The transfer of learning from local stereopsis to global stereopsis is compatible with an interacting two-stage model.