AUTHOR=Korchut Agnieszka , Rejdak Konrad 

TITLE=Late neurological consequences of SARS-CoV-2 infection: New challenges for the neurologist

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 17 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1004957

DOI=10.3389/fnins.2023.1004957

ISSN=1662-453X

ABSTRACT=.Objective: To study the frequency of neurological symptoms and diseases in 
COVID-19 adult patients that may be late consequences of SARS-CoV-2 infection in a systematic review of the literature.

Methods: Relevant studies were identified through electronic explorations of Scopus, PubMed, Google Scholar. We followed PRISMA guidelines. Data were collected from studies where the diagnosis of COVID-19 was confirmed and its late neurological consequences occurred  at least 4 weeks after initial  SARS-CoV-2 infection. Review articles were excluded from the study. Neurological manifestations were stratified on the basis of  the frequency (above 5%, 10%, 20%) where number of studies and sample size were significant.

Results: A total of 497 articles were identified for eligible content. This paper provides relevant information from 45 studies involving 9 746 patients.
Fatigue, cognitive problems, smell and taste dysfunctions were the most frequent reported long-term neurological symptoms in COVID-19 patients. Other common neurological issues were paresthesia, headache and dizziness. 

Conclusion: On a global scale of COVID-19 affected patients, prolonged neurological problems have become increasingly recognized and concerning.
Our review might be an additional source of knowledge about potential 
long-term neurological impacts.