AUTHOR=Wang Rui , Yan Yiquan , Tie Yateng , Zhang Qi , Pan Yikai , Li Shuhan , Fan Jieyi , Li Chengfei , Li Xi , Wang Yongchun , Sun Xiqing , Zhang Tongmei , Zhao Xingcheng 

TITLE=Hypoxic acclimatization training improves the resistance to motion sickness

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 17 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1216998

DOI=10.3389/fnins.2023.1216998

ISSN=1662-453X

ABSTRACT=Objective: Vestibular provocation is one of the main causes of flight illusions and its occurrence is closely related to the susceptibility of motion sickness (MS). However, existing training programs have limited effect on improving the resistance to motion sickness. In this study, we investigated the effects of hypoxia acclimatization training (HAT) on the resistance to motion sickness.: Healthy military college students were identified as subjects according to the criteria. MS model was induced by a rotary chair. Experimental groups included control, HAT, 3D roller training (3DRT) and combined training. Results: The Graybiel scores were decreased in the HAT group and in 3DRT group, and further decreased in the combined training group in MS induced by rotary chair. Participants had significant increase in blood pressures after rotary chair test and significant increase in heart rate during rotary chair test, but these changes disappeared in all three training groups. Additionally, LFn was increased and HFn was decreased, and LF/HF was increased accordingly during rotary chair test in control group. But the changes of these three parameters are completely opposite in three training groups during rotary chair test. Compared with control group, the decreasing changes in pupillary contraction velocity (PCV) and pupillary minimum diameter (PMD) of three training groups were smaller. In particular, the binocular PCV changes were further attenuated in the combined training group. Conclusion: Our research provides a possible candidate solution for training military pilots in the resistance to motion sickness.