AUTHOR=Zhang Kang , Li Kexin , Zhang Chunyun , Li Xiaodong , Han Shuai , Lv Chuanxiang , Xie Jingwei , Xia Xiaoyu , Bie Li , Guo Yongkun 

TITLE=The accuracy of different mismatch negativity amplitude representations in predicting the levels of consciousness in patients with disorders of consciousness

JOURNAL=Frontiers in Neuroscience

VOLUME=Volume 17 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1293798

DOI=10.3389/fnins.2023.1293798

ISSN=1662-453X

ABSTRACT=The mismatch negativity (MMN) index has been used to evaluate consciousness levels in patients with disorders of consciousness (DoC). Indeed, MMN has been validated for the diagnosis of vegetative state/unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state (MCS). In this study, we evaluated the accuracy of different MMN amplitude representations in predicting levels of consciousness. Task-state electroencephalography (EEG) data were obtained from 67 patients with DoC (35 VS and 32 MCS). We performed a microstate analysis of the task-